THE CHROMATIN VIROLOGY LAB

Publications

Human cytomegalovirus induces neuronal gene expression through IE1 for viral maturation

Laurel E. Kelnhofer-Millevolte, Julian R. Smith, Daniel H. Nguyen, Lea S. Wilson, Hannah C. Lewis, Edward A. Arnold, Mia R. Brinkley, Kihye Shin, Jin-Hyun Ahn, Eui Tae Kim, Katarzyna Kulej, Adam P. Geballe, Srinivas Ramachandran & Daphne C. Avgousti

Nature Communications, 2025

DOI PMID

Post-translational modifications on protein VII are important during the early stages of adenovirus infection

Edward A Arnold, Julian R Smith, Katie Leung, Daniel H Nguyen, Laurel E Kelnhofer-Millevolte, Monica S Guo, Jason G Smith, Daphne C Avgousti

Journal of Virology, 2024

DOI PMID

Viral imitation is the sincerest form of epigenetic flattery

Julian R Smith, Angela A Arellano, Daphne C Avgousti

Molecular Biology of the Cell, 2024

DOI PMID

Controlling much? Viral control of host chromatin dynamics

Laurel E Kelnhofer-Millevolte, Edward A Arnold, Daniel H Nguyen, Daphne C Avgousti

Annual Reviews Virology, 2024

DOI PMID

Adenovirus protein VII binds the A-box of HMGB1 to repress interferon responses

Edward A Arnold, Robin J Kaai, Katie Leung, Mia R Brinkley, Laurel E Kelnhofer-Millevolte, Monica S Guo, Daphne C Avgousti

PLoS Pathogens, 2023

DOI PMID

HSV-1 exploits host heterochromatin for nuclear egress

Hannah C Lewis, Laurel E Kelnhofer-Millevolte, Mia R Brinkley, Hannah E Arbach, Edward A Arnold, Saskia Sanders, Jens B Bosse, Srinivas Ramachandran, Daphne C Avgousti

Journal of Cell Biology, 2023

DOI PMID

Virology under the microscope—a call for rational discourse

Goodrum F, Lowen AC, Lakdawala S, Alwine J, Casadevall A, Imperiale MJ, Atwood W, Avgousti DC, Baines J, Banfield B, Banks L, Bhaduri-McIntosh S, Bhattacharya D, Blanco-Melo D, Bloom D, Boon A, Boulant S, Brandt C, Broadbent A, et al.

Published concurrently in mSphere, mBio and Journal of Virology, 2023

DOI PMID

A viral histone-like protein exploits antagonism between linker histones and HMGB proteins to obstruct the cell cycle

Lynch KL, Dillon MR, Bat-Erdene M, Lewis HC, Kaai RJ, Arnold EA, Avgousti DC.

Current Biology, 2021

DOI PMID

STAT3–BDNF–TrkB signalling promotes alveolar epithelial regeneration after lung injury

Andrew J Paris, Katharina E Hayer, Joseph H Oved, Daphne C Avgousti, Sushila A Toulmin, Jarod A Zepp, William J Zacharias, Jeremy B Katzen, Maria C Basil, Madison M Kremp, April R Slamowitz, Sowmya Jayachandran, Aravind Sivakumar, Ning Dai, Ping Wang, David B Frank, Laurence C Eisenlohr, Edward Cantu III, Michael F Beers, Matthew D Weitzman, Edward E Morrisey, G Scott Worthen

Nature Cell Biology, 2020

DOI PMID

Epigenetics and the dynamics of chromatin during adenovirus infections

Lynch KL, Gooding LR, Garnett-Benson C, Ornelles DA, Avgousti DC.

FEBS Letters, 2019

DOI PMID

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